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Reference Laboratory Tests
41336
JC Polyoma Virus DNA, Qualitative Real-Time PCR
JC Virus is the cause of progressive multifocal leukoencephalopathy (PML), a severe demyelinating disease of the central nervous system. PML is a particular concern for individuals infected with the human immunodeficiency virus. The detection of JC virus DNA is based upon the real-time PCR amplification and detection of specific JC virus genomic sequences from total DNA extracted from the specimen.
This test is not approved for New York patient testing.
Methodology
Real-Time PCR
Reference Range
Not detected
Preferred Specimen
0.7 mL CSF, urine, serum or plasma (EDTA, ACD) (minimum 0.3 mL)
Transport Temperature
FROZEN on dry ice via overnight transport.
Results Available
1 to 3 days
CPT Code
87798
41446
JC Polyoma Virus DNA, Quantitative Real-Time PCR
JC Virus is the cause of progressive multifocal leukoencephalopathy (PML), a severe demyelinating disease of the central nervous system. PML is a particular concern for individuals infected with the human immunodeficiency virus. Quantification of JC virus DNA is based upon the real-time PCR amplification and detection of JCV genomic DNA. The quantitative range of this assay is 500 - 35,000,000 JCV DNA copies/mL.
This test is not approved for New York patient testing.
Methodology
Real-Time PCR
Reference Range
< 500 copies/mL
Preferred Specimen
0.7 mL CSF, plasma (EDTA, ACD), serum or urine
(minimum 0.3 mL)
Transport Temperature
FROZEN
Results Available
1 to 3 days
CPT Code
87799
43336
JC Virus DNA Qualitative Reflex to JC Virus DNA Quantitative
If JC Virus DNA is detected in the qualitative assay, the specimen will reflex
to JC Virus Quantitative PCR (Focus Unit Code 41446) for an additional charge.
The quantitative range of this assay is 500 - 35,000,000 JCV DNA copies/mL.
This test is not approved for New York patient testing.
Methodology
Real-Time PCR
Reference Range
Not Detected
Preferred Specimen
2 mL CSF, plasma (ACD or EDTA), or urine (minimum 1mL)
Transport Temperature
FROZEN
Results Available
2 to 3 days
CPT Code
87798 (Add 87799 if refle x ed)
43536
JC Virus DNA Ultrasensitive Quantitative Real-Time PCR
JC Virus is the cause of progressive multifocal leukoencephalopathy (PML), a severe demyelinating disease of the central nervous system. PML is a particular concern for individuals infected with the human immunodeficiency virus. This assay detects <50 COPIES/mL of JC virus DNA.
This test is not approved for New York patient testing.